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Heavy metals such as lead, cadmium, mercury, and arsenic have been implicated in the development of heart disease for decades. These toxic metals can substitute essential metals like iron and copper in the body, leading to impaired cell function. Heavy metals promote inflammation, free radical damage, and oxidative stress, which contribute to endothelial dysfunction—the initial stage of heart disease.
Coronary artery calcification, the build-up of calcium in the arteries, causes them to narrow, reducing blood flow to the heart and resulting in symptoms such as chest pain and breathlessness. This calcification can be reversed only with the help of EDTA chelation therapy, a treatment that uses EDTA to bind to heavy metals and facilitate their excretion from the body.
EDTA chelation therapy is not only effective for reversing coronary artery calcification but also has applications in treating other conditions associated with heavy metal toxicity, including:
Additionally, chelation therapy may support cancer treatment by:
Oral administration
Oral chelation refers to the administration of chelating agents through the mouth to bind and remove heavy metals and other toxins from the body. Unlike intravenous (IV) chelation therapy, which delivers chelating agents directly into the bloodstream, oral chelation relies on absorption through the digestive system.
Intravenous administration
An intravenous (IV) line is inserted into a vein, usually in the arm. A solution containing EDTA will be prepared. The dosage of EDTA is typically calculated based on the patient’s body weight and overall health condition. The EDTA solution is administered slowly through the IV line. The infusion can take anywhere from 1.5 to 3 hours, depending on the prescribed dose and patient tolerance.
A thorough medical evaluation has to be conducted to determine if the patient is a suitable candidate for EDTA chelation therapy. This includes a detailed medical history, physical examination, and laboratory tests to assess kidney function, liver function, and levels of heavy metals in the blood.
It is advised to stay well-hydrated before the procedure to help protect the kidneys and facilitate the excretion of chelated metals.
Ravalli F, Vela Parada X, Ujueta F, Pinotti R, Anstrom KJ, Lamas GA, Navas-Acien A. Chelation Therapy in Patients With Cardiovascular Disease: A Systematic Review. J Am Heart Assoc. 2022 Mar 15;11(6):e024648. doi: 10.1161/JAHA.121.024648. Epub 2022 Mar 1. PMID: 35229619; PMCID: PMC9075296.
Fulgenzi A, Ferrero ME. EDTA Chelation Therapy for the Treatment of Neurotoxicity. Int J Mol Sci. 2019 Feb 26;20(5):1019. doi: 10.3390/ijms20051019. PMID: 30813622; PMCID: PMC6429616.